Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023

Omer Taha Ahmed Elmukashfi; Taha Ahmed Elmukashfi Elsheikh; Ahmad Alamin Alshaikh; Afnan Abdelrahman Elsiddig Dafalla; Wala Osman Eltieb Omer; Asma Mohammed Warrag Omer; Osman Elfatih Elheber Omer; Eman Ali Ahmed Mohamed; Osman Merghani Osman Mahmoud

doi:doi:10.11648/j.jctr.20241201.13

Case Report |

Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023

Omer Taha Ahmed Elmukashfi^*, Taha Ahmed Elmukashfi Elsheikh, Ahmad Alamin Alshaikh, Afnan Abdelrahman Elsiddig Dafalla, Wala Osman Eltieb Omer, Asma Mohammed Warrag Omer, Osman Elfatih Elheber Omer, Eman Ali Ahmed Mohamed, Osman Merghani Osman Mahmoud

Published in Journal of Cancer Treatment and Research (Volume 12, Issue 1)

Received: 27 December 2023 Accepted: 6 January 2024 Published: 27 February 2024

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Abstract

Background: Primary breast lymphoma is a malignant lymphoma primarily involving breast in absence of previously detected lymphoma localizations. Method: A male of forty years old admitted to Department of Surgery; Wad Madani Teaching Hospital; Gezira State; Sudan; complaining of left breast lump for three months. Condition observed as a painful swelling in left breast, increasing gradually in size, associated with continuous high-grade fever, no rigors and relieved by analgesia, no nipple discharges. Had significant weight loss, anorexia, fatigability, back pain, dry cough with no hemoptysis, no history of headache, and no past or family history of similar condition. Examination: patient looks ill, pale, and not jaundiced. Breast examination: Left breast was larger than right one. Left breast: no nipple destruction, nipple was directed downward medially, no skin changes or dimpling, and no ulceration. There was a mass in left upper outer quadrant, measuring 6*7 cm, smooth surface, hard in consistency with well-defined edges, and attached to muscles but not to skin. No palpable axillary lymph nodes. Right breast was normal. Chest and abdominal examination were unremarkable. Investigations: Fine needle aspiration cytology showed poorly differentiated carcinoma. Incisional biopsy revealed: high grade Non-Hodgkins Lymphomas (Diffuse Large B Cell Lymphoma). He was referred to oncological department for neoadjuvant chemoradiotherapy. Conclusion and Recommendation: Primarily breast lymphoma is extremely rare among male, showing features mimicking breast carcinoma. Incisional biopsy was recommended for investigation of breast lump especially among males.

Published in	Journal of Cancer Treatment and Research (Volume 12, Issue 1)
DOI	10.11648/j.jctr.20241201.13
Page(s)	18-20
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Primary Breast Lymphoma Among Male, Wad Madani Teaching Hospital, Gezira State, Sudan

References

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[7]	Cheah C Y, Campbell B A, Seymour J F, et al, Primary breast lymphoma, Cancer Treat Rev 2014, http://dx.doi.org/10.1016/j.ctrv.2014.05.010
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[10]	Earnest R E, Downey D M, Fox J P, McKellar D P. Recurrence of Primary Breast Lymphoma in Contralateral Breast: Case Report and Review of the Literature, Journal of Surgical Education, 2008, 65(5), PP: (364-366).
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Elmukashfi, O. T. A., Elsheikh, T. A. E., Alshaikh, A. A., Dafalla, A. A. E., Omer, W. O. E., et al. (2024). Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023. Journal of Cancer Treatment and Research, 12(1), 18-20. https://doi.org/10.11648/j.jctr.20241201.13

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ACS Style

Elmukashfi, O. T. A.; Elsheikh, T. A. E.; Alshaikh, A. A.; Dafalla, A. A. E.; Omer, W. O. E., et al. Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023. J. Cancer Treat. Res. 2024, 12(1), 18-20. doi: 10.11648/j.jctr.20241201.13

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AMA Style

Elmukashfi OTA, Elsheikh TAE, Alshaikh AA, Dafalla AAE, Omer WOE, et al. Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023. J Cancer Treat Res. 2024;12(1):18-20. doi: 10.11648/j.jctr.20241201.13

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@article{10.11648/j.jctr.20241201.13,
  author = {Omer Taha Ahmed Elmukashfi and Taha Ahmed Elmukashfi Elsheikh and Ahmad Alamin Alshaikh and Afnan Abdelrahman Elsiddig Dafalla and Wala Osman Eltieb Omer and Asma Mohammed Warrag Omer and Osman Elfatih Elheber Omer and Eman Ali Ahmed Mohamed and Osman Merghani Osman Mahmoud},
  title = {Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023},
  journal = {Journal of Cancer Treatment and Research},
  volume = {12},
  number = {1},
  pages = {18-20},
  doi = {10.11648/j.jctr.20241201.13},
  url = {https://doi.org/10.11648/j.jctr.20241201.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jctr.20241201.13},
  abstract = {Background: Primary breast lymphoma is a malignant lymphoma primarily involving breast in absence of previously detected lymphoma localizations. Method: A male of forty years old admitted to Department of Surgery; Wad Madani Teaching Hospital; Gezira State; Sudan; complaining of left breast lump for three months. Condition observed as a painful swelling in left breast, increasing gradually in size, associated with continuous high-grade fever, no rigors and relieved by analgesia, no nipple discharges. Had significant weight loss, anorexia, fatigability, back pain, dry cough with no hemoptysis, no history of headache, and no past or family history of similar condition. Examination: patient looks ill, pale, and not jaundiced. Breast examination: Left breast was larger than right one. Left breast: no nipple destruction, nipple was directed downward medially, no skin changes or dimpling, and no ulceration. There was a mass in left upper outer quadrant, measuring 6*7 cm, smooth surface, hard in consistency with well-defined edges, and attached to muscles but not to skin. No palpable axillary lymph nodes. Right breast was normal. Chest and abdominal examination were unremarkable. Investigations: Fine needle aspiration cytology showed poorly differentiated carcinoma. Incisional biopsy revealed: high grade Non-Hodgkins Lymphomas (Diffuse Large B Cell Lymphoma). He was referred to oncological department for neoadjuvant chemoradiotherapy. Conclusion and Recommendation: Primarily breast lymphoma is extremely rare among male, showing features mimicking breast carcinoma. Incisional biopsy was recommended for investigation of breast lump especially among males.
},
 year = {2024}
}

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TY - JOUR
T1 - Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023
AU - Omer Taha Ahmed Elmukashfi
AU - Taha Ahmed Elmukashfi Elsheikh
AU - Ahmad Alamin Alshaikh
AU - Afnan Abdelrahman Elsiddig Dafalla
AU - Wala Osman Eltieb Omer
AU - Asma Mohammed Warrag Omer
AU - Osman Elfatih Elheber Omer
AU - Eman Ali Ahmed Mohamed
AU - Osman Merghani Osman Mahmoud
Y1 - 2024/02/27
PY - 2024
N1 - https://doi.org/10.11648/j.jctr.20241201.13
DO - 10.11648/j.jctr.20241201.13
T2 - Journal of Cancer Treatment and Research
JF - Journal of Cancer Treatment and Research
JO - Journal of Cancer Treatment and Research
SP - 18
EP - 20
PB - Science Publishing Group
SN - 2376-7790
UR - https://doi.org/10.11648/j.jctr.20241201.13
AB - Background: Primary breast lymphoma is a malignant lymphoma primarily involving breast in absence of previously detected lymphoma localizations. Method: A male of forty years old admitted to Department of Surgery; Wad Madani Teaching Hospital; Gezira State; Sudan; complaining of left breast lump for three months. Condition observed as a painful swelling in left breast, increasing gradually in size, associated with continuous high-grade fever, no rigors and relieved by analgesia, no nipple discharges. Had significant weight loss, anorexia, fatigability, back pain, dry cough with no hemoptysis, no history of headache, and no past or family history of similar condition. Examination: patient looks ill, pale, and not jaundiced. Breast examination: Left breast was larger than right one. Left breast: no nipple destruction, nipple was directed downward medially, no skin changes or dimpling, and no ulceration. There was a mass in left upper outer quadrant, measuring 6*7 cm, smooth surface, hard in consistency with well-defined edges, and attached to muscles but not to skin. No palpable axillary lymph nodes. Right breast was normal. Chest and abdominal examination were unremarkable. Investigations: Fine needle aspiration cytology showed poorly differentiated carcinoma. Incisional biopsy revealed: high grade Non-Hodgkins Lymphomas (Diffuse Large B Cell Lymphoma). He was referred to oncological department for neoadjuvant chemoradiotherapy. Conclusion and Recommendation: Primarily breast lymphoma is extremely rare among male, showing features mimicking breast carcinoma. Incisional biopsy was recommended for investigation of breast lump especially among males.

VL - 12
IS - 1
ER -

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Author Information

Omer Taha Ahmed Elmukashfi

General Surgery Council, Sudan Medical Specialization Board, Khartoum, Sudan

Contact Email
Taha Ahmed Elmukashfi Elsheikh

Department of Community Medicine, Faculty of Medicine, University of Khartoum, Khartoum, Sudan
Ahmad Alamin Alshaikh

Department of General Surgery, Faculty of Medicine, University of Gezira, Wad Madani, Sudan
Afnan Abdelrahman Elsiddig Dafalla

Department of Training, Federal Ministry of Health, Khartoum, Sudan
Wala Osman Eltieb Omer

General Surgery Council, Sudan Medical Specialization Board, Khartoum, Sudan
Asma Mohammed Warrag Omer

National Cancer Institute (NCI), University of Gezira, Wad Madani, Sudan
Osman Elfatih Elheber Omer

General Surgery Council, Sudan Medical Specialization Board, Khartoum, Sudan
Eman Ali Ahmed Mohamed

Department of General Surgery, Faculty of Medicine, University of Gezira, Wad Madani, Sudan
Osman Merghani Osman Mahmoud

Department of General Surgery, Fajer Medical College, Khartoum, Sudan

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APA Style

Elmukashfi, O. T. A., Elsheikh, T. A. E., Alshaikh, A. A., Dafalla, A. A. E., Omer, W. O. E., et al. (2024). Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023. Journal of Cancer Treatment and Research, 12(1), 18-20. https://doi.org/10.11648/j.jctr.20241201.13

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ACS Style

Elmukashfi, O. T. A.; Elsheikh, T. A. E.; Alshaikh, A. A.; Dafalla, A. A. E.; Omer, W. O. E., et al. Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023. J. Cancer Treat. Res. 2024, 12(1), 18-20. doi: 10.11648/j.jctr.20241201.13

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AMA Style

Elmukashfi OTA, Elsheikh TAE, Alshaikh AA, Dafalla AAE, Omer WOE, et al. Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023. J Cancer Treat Res. 2024;12(1):18-20. doi: 10.11648/j.jctr.20241201.13

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@article{10.11648/j.jctr.20241201.13,
  author = {Omer Taha Ahmed Elmukashfi and Taha Ahmed Elmukashfi Elsheikh and Ahmad Alamin Alshaikh and Afnan Abdelrahman Elsiddig Dafalla and Wala Osman Eltieb Omer and Asma Mohammed Warrag Omer and Osman Elfatih Elheber Omer and Eman Ali Ahmed Mohamed and Osman Merghani Osman Mahmoud},
  title = {Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023},
  journal = {Journal of Cancer Treatment and Research},
  volume = {12},
  number = {1},
  pages = {18-20},
  doi = {10.11648/j.jctr.20241201.13},
  url = {https://doi.org/10.11648/j.jctr.20241201.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jctr.20241201.13},
  abstract = {Background: Primary breast lymphoma is a malignant lymphoma primarily involving breast in absence of previously detected lymphoma localizations. Method: A male of forty years old admitted to Department of Surgery; Wad Madani Teaching Hospital; Gezira State; Sudan; complaining of left breast lump for three months. Condition observed as a painful swelling in left breast, increasing gradually in size, associated with continuous high-grade fever, no rigors and relieved by analgesia, no nipple discharges. Had significant weight loss, anorexia, fatigability, back pain, dry cough with no hemoptysis, no history of headache, and no past or family history of similar condition. Examination: patient looks ill, pale, and not jaundiced. Breast examination: Left breast was larger than right one. Left breast: no nipple destruction, nipple was directed downward medially, no skin changes or dimpling, and no ulceration. There was a mass in left upper outer quadrant, measuring 6*7 cm, smooth surface, hard in consistency with well-defined edges, and attached to muscles but not to skin. No palpable axillary lymph nodes. Right breast was normal. Chest and abdominal examination were unremarkable. Investigations: Fine needle aspiration cytology showed poorly differentiated carcinoma. Incisional biopsy revealed: high grade Non-Hodgkins Lymphomas (Diffuse Large B Cell Lymphoma). He was referred to oncological department for neoadjuvant chemoradiotherapy. Conclusion and Recommendation: Primarily breast lymphoma is extremely rare among male, showing features mimicking breast carcinoma. Incisional biopsy was recommended for investigation of breast lump especially among males.
},
 year = {2024}
}

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VL - 12
IS - 1
ER -

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